KICKOFF: 8:15 p.m. ET
KEY FACTS: The matchup pits youth versus experience in two key spots: Quarterback (Kenny Pickett vs. Matt Ryan) and coach (Jeff Saturday vs. Mike Tomlin). The Colts are 2-0 ATS under Saturday but caught points in both. This is Pickett’s first appearance on MNF; Ryan is 6-7.
TRENDING: The Steelers have lost four straight road games since their Week 1 overtime victory over Cincinnati. The Under has hit in 14 of Indy’s last 16 games.