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Chiefs (-1) @ 49ers; Total 49

October 23, 2022

KICKOFF: 4:25 p.m. ET

KEY FACTS: The Niners are the talk of the NFL after landing RB Christian McCaffrey, who is expected to make his debut Sunday (Rushing Yards Total: 30.5). SF is also getting healthier, adding DE Nick Bosa and LT Trent Williams to its lineup. JuJu Smith-Schuster came alive last week (5 catches, 113 yards), giving Patrick Mahomes a target he craves.

TRENDING: Jimmy Garoppolo is 16-4 ATS as a ‘dog, and the Niners have covered six straight following a loss.

INSIGHT: The line has dipped from 2.5 even though the Chiefs are a massive public favorite – 81% of tickets, 75% of handle.